Gastroprotective Effect of Borago Extracts against Indomethacin-Induced Gastric Ulcer in Rats
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چکیده
منابع مشابه
Gastroprotective effect of sodium hydrosulfide against indomethacin-induced gastric ulcer in diabetic rats
Introduction: The incidence rate of gastric erosions and ulcers in diabetic patients are higher due to failure of mucosal antioxidant defense and maintain enough blood flow. The present study evaluated the gastro-protective effect of sodium hydrosulfide (NaHS) against indomethacin-induced gastric lesions in diabetic rats. Methods: In order to test anti-ulcer activity of NaHS against indomet...
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The gastroprotective effect of the different fractions of Tribulusterrestris L. was investigated in the indomethacininduced gastric ulcer in rats at dose of 30 mg/kg body weight. The petroleum ether and aqueous fractions hada significant gastroprotective activity, while the chloroform and ethyl acetate fractions hada moderate gastroprotective activity. Keyword: Tribulusterrestris, Zygophyllacea...
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Objectives: Free radicals generation, inflammation, and nitric oxide (NO) modulation are involved in indomethacin (IND)-induced gastric ulcers. Most of the drugs used for the treatment of gastric ulcer have various side effects. Genistein (GEN), the natural isoflavones isolated from soya bean has an antioxidant, anti-inflammatory, and NO modulating activity. These properties could make GEN a pr...
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متن کاملGastroprotective Effect of L-Carnitine on Indomethacin-Induced Gastric Ulcer in Rats: The Involvement of Antioxidant Mechanisms and Nitric Oxide
This study investigated the gastroprotective effect of Lcarnitine against indomethacin-induced gastric ulcer in rats and the possible mechanisms underlying this effect. Two sets of experiments were performed. In the first set male albino rats (170-210 g) were randomly allocated into a normal control group, ulcer control group (received a single dose of indomethacin 30 mg/kg po) and three ulcer ...
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ژورنال
عنوان ژورنال: Journal of Food and Dairy Sciences
سال: 2018
ISSN: 2090-3731
DOI: 10.21608/jfds.2018.77776